ea0026p172 | Neuroendocrinology | ECE2011
Ianas O
, Manda D
, Heltianu C
, Vladoiu S
, Popa O
, Rosca R
, Oros S
, Covic M
, Joja O
Background: Genetic variants of the endothelial nitric oxide synthase (eNOS) gene have been reported to be associated with vascular disease. We hypothesized that G894T polymorphism might trigger many of the endocrine-metabolic cognitive changes related to aging.Study design: One hundred and eighty subjects aged 5580+ years with moderately cognitive impairment (MCI) (MMSE<28) (lot 1), 140 age-matched subjects without cognitive impairment (MMSE&#...